Clinical strategies for the early detection and prevention of intracranial aneurysms [Estrategias clínicas para la detección temprana y prevención de aneurisma intracraneales]
DOI:
https://doi.org/10.62574/pmx4th84Keywords:
aneurysm, aneurysm dissecting, intracranial aneurysmAbstract
Objective: to analyse clinical strategies for the early detection and prevention of intracranial aneurysms. Method: Systematic review of 15 scientific articles. Results: Early detection and prevention of intracranial aneurysms require a multidisciplinary approach that integrates screening strategies in high-risk populations, interventions targeting genetic and metabolic factors, and the use of advanced endovascular techniques. The identification of molecular biomarkers, such as inflammation and oxidative stress, together with innovative tools such as macrophage imaging and polygenic risk scores, represent promising advances for improving risk stratification and personalising clinical management.
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Pontes FGB, da Silva EM, Baptista-Silva JC, Vasconcelos V. Treatments for unruptured intracranial aneurysms. Cochrane Database Syst Rev. 2021;5(5):CD013312. Published 2021 May 10. doi:10.1002/14651858.CD013312.pub2
Rinkel GJ, Ruigrok YM. Preventive screening for intracranial aneurysms. Int J Stroke. 2022;17(1):30-36. doi:10.1177/17474930211024584
Xu Z, Rui YN, Hagan JP, Kim DH. Intracranial Aneurysms: Pathology, Genetics, and Molecular Mechanisms. Neuromolecular Med. 2019;21(4):325-343. doi:10.1007/s12017-019-08537-7
Laurent D, Small C, Lucke-Wold B, et al. Understanding the genetics of intracranial aneurysms: A primer. Clin Neurol Neurosurg. 2022;212:107060. doi:10.1016/j.clineuro.2021.107060
Li H, Xu H, Li Y, et al. Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms. Nat Commun. 2020;11(1):3218. Published 2020 Jun 25. doi:10.1038/s41467-020-16990-3
Nielsen R, Hauerberg J, Munthe S, et al. Ugeskr Laeger. 2019;181(2):V05180375.
Pan T, Shi Y, Yu G, Mamtimin A, Zhu W. Intracranial Aneurysms and Lipid Metabolism Disorders: From Molecular Mechanisms to Clinical Implications. Biomolecules. 2023;13(11):1652. Published 2023 Nov 14. doi:10.3390/biom13111652
Etminan N, Dörfler A, Steinmetz H. Unruptured Intracranial Aneurysms- Pathogenesis and Individualized Management. Dtsch Arztebl Int. 2020;117(14):235-242. doi:10.3238/arztebl.2020.0235
Sarkodie BD, Jimah BB, Mohammed AH, et al. Intracranial aneurysms in Ghanaian adults. Ghana Med J. 2023;57(3):250-255. doi:10.4314/gmj.v57i3.13
Shimizu K, Kushamae M, Aoki T. Macrophage Imaging of Intracranial Aneurysms. Neurol Med Chir (Tokyo). 2019;59(7):257-263. doi:10.2176/nmc.st.2019-0034
Olsen KH, Bendix EF, Bjarkam CR. Ugeskr Laeger. 2019;181(50):V08190448.
Briganti F, Leone G, Marseglia M, et al. Endovascular treatment of cerebral aneurysms using flow-diverter devices: A systematic review. Neuroradiol J. 2015;28(4):365-375. doi:10.1177/1971400915602803
Løvik K, Laupsa-Borge J, Logallo N, Helland CA. Dyslipidemia and rupture risk of intracranial aneurysms-a systematic review. Neurosurg Rev. 2021;44(6):3143-3150. doi:10.1007/s10143-021-01515-3
Bhaisora KS, Behari S, Godbole C, Phadke RV. Traumatic aneurysms of the intracranial and cervical vessels: A review. Neurol India. 2016;64 Suppl:S14-S23. doi:10.4103/0028-3886.178032
Frerich S, Cole JW. Novel Polygenic Risk Score for Intracranial Aneurysms. Stroke. 2023;54(3):819-820. doi:10.1161/STROKEAHA.122.041807
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